In research conducted by an independent research lab, 3 clinical tests were conducted on a total of 120 subjects. Various subjects were tested at time points of 2, 4, 8 and 12 weeks. Results were measured by clinical expert grading, digital photography and subject assessment. Additional skin biopsy analysis and in vitro skin equivalents (cultured cells) assessed markers of skin health such as: collagen stimulation, barrier integrity and NAD content. The manuscript for these trials is in progress for publication.